Discovery of Kite-O-San (Chitosan)

Chitosan, pronounced as ‘Kite-O-San’ was believed to be a ‘fat magnet’, but in reality is simply a fat inhibitor as researchers have proved it.

It is useful for people who want to find the best way of losing fat. It is a substance that is removed from chitin that is obtained in exoskeletons of crustaceans. You must be thinking how it is helpful and how it may be processed – Chitosan is processed by taking the shells clear of the sea animals such as lobster, shrimps and crabs

Another question arises here is that how was it found and how it can be utilized – we are going to discuss it here. It was introduced in 1811 when chitin was discovered. The fact about the chitin was revealed by Braconn. He was professor of the natural history in France. He actually was performing search about mushrooms and he isolated something named as chitin after sometime. After about twenty years, another researcher revealed that it is also present in insects and some plants as well. The name chitin is derived from Greek word, i.e. tunic or envelope. The idea was further elaborated in 1843 by Lassaigne. He was demonstrating the occurrence of nitrogen in Chitosan.

After the discovery of chitin, the name ‘chitosan’ came forth. It was initially revealed by Rouget whilst testing different things with chitin. Under the circumstances, Rouget learned that the compound of chitin may be controlled through chemical as well as temperature interventions for it to be fat-soluble.  After that, in 1878 Ledderhose acknowledged chitin to be resulting from glucosamine laterally with acetic acid – it was not in fact until 1894 that Hoppe-Seyler acknowledged the oriented chitin, chitosan.

In the commencement of twentieth century, a number of studies and searches considered chitosan as their style of schoolwork. After that, they implied roots of chitin, taking crab shells alongside with fungai. In 1930, Rammelberg’s investigates headed to the authentication on the distinctiveness of chitosan from these sources. What is more, it was distinguished that by hydrolyzing Chitosan in several modes, it was determined by individuals that chitin is a polysaccharide of glucosamine.  In 1950s, the application of x-ray examination had promoted the learning of the presence of chitin or chitosan in fungi. Though, it is simply the most highly developed technologies that demonstrated the most respected in keying out the occurrence of chitin in addition to cellulose in the cell walls.

In the start of sixties, chitosan was tested for its capability to attach with the red blood cells. Afterward, the matter of Chitosan was conceived and studied as a hemostatic agent. After that, for over three decades, it has been applied at water sanitization plants for detoxifying water. It is put on the shell where it soaks up greases, oils, in addition to other prospective toxins. These days, Chitosan is accepted as a nutritional appendage that is fantastic for weight loss.

The Lies About “Chitosan Fat Blocker”

What’s The Truth Behind The “Chitosan Fat Blocker”?

Numerous companies have claimed that chitosan is one of the most effective fat burners. In fact, it makes big promises of absorbing fat and preventing it from getting in your body, looking at it as the definitive fat blocker.  But does “chitosan fat blocker” really live up to it’s name?

chitosan fat blocker

It is important to know that whether chitosan is safe or effective as diet aid remains a controversy till date. Probably you’ve heard a great deal of claims regarding the advantages of chitosan. Many people have said that chitosan does work, but these claims contradict what few studies imply. Thorough clinical studies on humans have indicated that chitosan does NOT work!

One of the ordinarily cited studies on chitosan by the marketers and manufacturers of chitosan-based products is the 1994 ARS Medicina (Helsinki) Report. In this research, it was determined that test subjects lost eight percent of fatty tissue and reduced cholesterol by thirty-two percent in four weeks. Secondly, there are various studies on chitosan which revealed that the substance lowers plasma cholesterol and triglycerides and improved the HDL cholesterol level.

Evidence Supporting the “Chitosan Fat Blocker”?

Looking at these bits of evidence, one may be suitably convinced that chitosan’s claims are true. Nonetheless, when taking the designs of the studies on chitosan into account, the evidence appears in a much different light.

For instance, the 1994 ARS Medicina Report and others that support it appear to be loosely designed. Experts have noted that simply uncontrolled and anecdotal evidence seems to be the sole available evidence in research up to date.

Furthermore, most of other cholesterol lowering evidences reported in other resources are attained in another noteworthy fashion. The fact is, the majority of the studies on chitosan were conducted on mice, canines, guinea pigs, and broiler chickens.  There is in fact a nonexistence of studies on chitosan conducted on humans.

It is most unfortunate that only one well-designed study on chitosan, containing humans as subject, has been published.  That study was conducted in 1999 by the European Journal of Clinical Nutrition, displaying that chitosan supplements were no superior than a placebo in decreasing body weight.  There was a total of 34 overweight subjects were actually involved in the study.

They were apportioned to either a ‘ treatment group’ which received 4 capsules of chitosan twice a day for 28 days, or to a ‘placebo group’ which received a placebo under the same circumstances. After days of medicine, the results discovered no significant difference between two groups on any of the body mass index, serum cholesterol, triglycerides, Vitamins A, D, E or beta-carotene levels.  This is what actually led weight loss experts to agree that Chitosan does not work.

Conclusion About The “Chitosan Fat Blocker”

Further studies on chitosan were conducted, but all of them, nonetheless, have indicated that “chitosan fat blocker” did NOT block fat. As you might notice, these studies on chitosan have the identical determinations as the European Journal research. The worse part is chitosan has been shown to block some vitamins and minerals.

What the advertisements are saying appear to be media hype and thus the search for a miracle dietary supplement continues.

Chitosan Affect Blood Lipids In A Negative Way?

Chitosan Affect Blood Lipids

Chitosan Affect Blood Lipids In A Negative Way?  With the progression of time we human beings have become more lethargic in our physical activity which has led to extra fat getting accumulated in our body which in turn leads to obesity.

Chitosan is probably one of the most useful products helping in lowering extra fats. It is used as a weight loss facilitator. It is also thought of as cholesterol lowering mediator. The effect of chitosan on body fat has been studied over many decades. Many reports claim that regular chitosan ingestion helps reduce serum cholesterol levels and improve ratio of high density to little density lipoproteins that is well recognized to be defensive against cardiovascular diseases. Chitosan is known to lower cholesterol, also there are many claims that chitosan affects blood lipids.

Chitosan is derived from deacetylation of chitin, which is identical to cellulose available in the external shells of insects. The insects include crabs, lobsters and crustaceans. The fungal cell walls also fall in this category. Unlike the majority plant fibers, chitosan is known for possessing positively charged amino groups. These groups create ionic bonds with lipids along with bile elements.

The system is almost certainly intermediated by the effect of chitosan on micelle formation in the gut. It is in reality the lipid carrier and as per a couple of experts, the varied micelles in the gastrointestinal area enclose free fatty acids, cholesterol and other elements. Furthermore, it one of the ways of getting the lipids ingested into the bloodstream.  Imaginably what defends the scheme of chitosan disturbing blood lipids is the fact that chitosan functions by clipping to the complimentary fatty acids together with bile acid elements, thus disaffecting them from the micelles and isolating the incorporation of lipids.

Scientific studies disclose the actual score of chitosan affecting blood lipids.

Chitosan Affect Blood Lipids

Chitosan Affect Blood Lipids

The researches were continued in both animals as well as humans. The results have usually been more striking in different animal examples. Maybe this is as a result of higher chitosan ingestion in a lot of the researches. Several of the researches also demonstrate extremely remarkable diminutions on cholesterol  – LDL cholesterol levels.

Different researches conducted have collected effects that have been less straightforward, while several still indicate positive results.  One trustworthy research carried to understand if the claims on chitosan affecting blood lipids are factual is the actual placebo-controlled, double-blind research. The specific research had noted that there was an important decline in LDL cholesterol between subjects taking 2,4000 milligrams of chitosan every day, equated with placebo matters.

Alternatively, it was found that chitosan had no noteworthy result on the serum or on HDL, nonetheless it somewhat amplified triglycerides.

Other studies have accounted parallel and related lipid outcomes, however others have described that the claims on chitosan affecting blood lipids are on no account applicable. Perhaps, these disputes are as a result of the main difference in the dosage of chitosan given.

Read About Chitosan Fat Blocker

Natrol Inc’s Natrol Chitosan – the high quality weight loss supplement

Uncompromised quality of Natrol Chitosan makes it different and extraordinary product compared to other products in the market. This has made Natrol Chitosan one of the most significant weight reducing products. It is also composed of chitin as the principle ingredient like a few other Chitosan products. It offers good capability to stop the fat assimilation in human digestive tract. This medicinal product has been advertised heavily as a fat magnet at different forums like television, newspapers and internet etc.

It is claimed by makers of Natrol Chitosan that it is one the finest supplement for extra weight loss. This product is in reality created by Natrol, Inc. and so is the name given to it. Natrol, Inc. located in Southern California is one of the well known businesses producing nutritional supplements including Natrol Chitosan. In point of fact, this company not only manufactures but also advertises its high quality and branded Chitosan supplements. This manufacturing company is now producing its own Natrol Chitosan capsules along with many other weight controlling tablets.

Presently, it is one of the easily obtainable fat burning supplements in the market. Most of numerous other products termed as fat magnets usually fail to get the magnificent results offered by Natrol Chitosan. Take only two meals with heavy fats in a day to get optimum and better results out of Natrol Chitosan.

Amount of supplements consists of the accessible series of Natrol’s Chitosan. One or more of the renowned and heavily purchased products of this series is Natrol Chitosan of 500mg. It is probably one of the most common dietary supplements as the source of organic fiber as reported by several reviewers. This dietary supplement is quite effective and is much simple to be swallowed. This Natrol Chitosan comprises about 95% of deacetylated Chitosan to enhance its solubility capacity. What is more, it is all-natural product with no wheat, milk, yeasts and glutens etc. Furthermore, it is recommended that people allergic of seafood particularly sea shell must not take Natrol Chitosan to lower their weight. For this purpose, always try not to use such fat taking out products as per your doctor’s prescription.

It is advised by diet and health specialists to use Chitosan containing products after conferring with a health care specialist. It should not also be brought into play by expectant women. It is in addition worth noting that Natrol Chitosan should not be used before any exercise or beginning of the weight loss program. In addition, fat soluble minerals including A, E and K must not be taken together with Chitosan based products. Heavy people do not forget to take right dose of this product mainly derived from Chitosan. The recommended dose of Natrol Chitosan is 3 capsules before each fat containing meal.

Natrol is regularly broadening its perspective and scope using formulating and producing innovative Natrol Chitosan. This cutting edge product brings much better quality specifically in the life of heavy people. Natrol, Inc. is constantly producing the unparalleled and high quality fat controlling supplements fundamentally made from Chitosan. It is also manufacturing numerous other health related products.

Possible Side Effects of Chitosan

What Is Chitosan Used For?

According to manufacturers and users, chitosan is fantastic for weight loss as it binds fat to molecules in the digestive tract, preventing the body from absorbing the fat. It in addition lowers the cholesterol in the blood, treat anemia, and improve the individual’s strength, the immunity process, as well as the appetite and sleep. Also reported is that chitosan can help treat tooth and gum infections and help tissue healing after plastic surgery.

Nonetheless, whether chitosan is effective for treating such mentioned conditions or safe as a diet aid still remains controversial. It is oftentimes the subject of most debates regarding weight reduction. Some say that there are adverse side outcomes of chitosan, while others have indicated evidences that contradict such belief.

Long-Term/Permanent Side Effects of Chitosan

There are still no long-term studies of the side effects of chitosan on human health since most of the studies were conducted on animals. Nonetheless, if we’ll look at those animal studies and the first published 1999 clinical trial done on humans, results suggest that chitosan could inhibit the absorption of minerals and fat soluble vitamins. Also, studies have revealed certain adverse side effects of chitosan in pregnant women, particularly on the growth of the fetus and the outcome of pregnancy.

Experts also determined other minor outcomes of chitosan. These possible ill effects may include respiratory health issues or tightness in your chest or throat, in addition to chest pain and skin hives, rash, or itchy or swollen skin. Other possible side results of chitosan are headaches and swollen heels and wrists.

Short-Term Side Effects of Chitosan

side effects of chitosan

With all those talked about possible side effects, it’s no wonder that experts highly recommend to stop taking your medicine immediately and speak to your physician if you’ve any of the mentioned ill effects. The excuse for the medicine to be causing such symptoms is it might indicate that you are allergic to chitosan-based products.

So perhaps the best that you can do to look after yourself and your well being is to inform your healthcare professional before taking any chitosan-based products about your current medicine. Tell your doctor if you are taking medicine or are allergic to any medicine, or if you are pregnant or going to conceive while using chitosan. This must also apply to those moms who are breastfeeding, as well as to individuals who have clotting problems and have any other health problem, such as high blood pressure or heart or blood vessel disease.

Speak with your caregiver about how much chitosan you should take. Note that an over dose of chitosan-based products may result in those possible side effects of chitosan. Just note that the quantity of chitosan highly depends on the strength of the medicine and the reason you are taking it. So, if you are taking this medicine without instructions from your caregiver, then follow the directions written on the label. To ensure that you are clear of the possible bad outcomes of chitosan, do not take more medicine or take it more often than the directions tell you to.

The Chemistry Of Chitosan – Chitosan Weight Loss Supplement Overview

Chitosan Weight Loss Supplement Overview

The wonderful properties of Chitosan weight loss supplement have attracted the attention of many people as a weight reduction supplement. Is it a chemical or a naturally available ingredient?

Actually the hard shell of crustaceans contains Chitosan, which is a significant polymer useful in supervising cholesterol and acting as a weight reduction supplement. Chitosan chemistry provide basis for its use in weight and cholesterol controlling products. Crustaceans are aquatic arthropods including shrimps, clams and lobsters etc. Chitosan polymer contained in outer shells of these arthropods make you think once before chucking out these shells, however it isn’t really possible to consume them as it is. This significant polymer is most commonly made use of in weight reduction supplements.

Furthermore, products used for cholesterol profile improvement generally contain chemically made fiber of Chitosan. Examination of Chitosan chemistry shows that it is a biopolymer sort of substance. This property makes it possible for manufacturers of cholesterol and weight controlling items to use Chitosan as basic ingredient. Chitosan chemistry involves numerous biomedical applications.

chitosan weight loss supplementFollowing are some of the most frequent biomedical applications involving the use of Chitosan weight loss supplement.

• Wound healing

• Tissue engineering

• Tissue repair

• Local delivery of cells etc

Analysis of Chitosan chemistry revealed that it is comprised of N-deacylation that is a chitin molecule. Chitosan is basically a linear polysaccharide, which is mainly composed of ß (1-4)-linked D-glucosamine together with N-Acetyl glucosamine monomers.

N-acetyl-D-glucosamine is acetylated unit (A) whereas D-glucosamine is a deacetylated unit (D). This chemical composition shows that Chitosan may be produced through the deacetylation of chitin on commercial basis. Chitin is the basic structural element present in the outer skeletons of crustaceans and this has been determined by resources of Chitosan chemistry. More often than not, NMR spectroscopy is used to check out the percentage of deacetylation in artificially prepared Chitosan. The deacetylation degree in commercially manufactured Chitosan falls in range of 60 to 100%.

A number of bio- research demonstrated that this significantly helpful substance is an excellent carrier of catalysts. Moreover, numerous resources of Chitosan chemistry depicts that Chitosan is a substance having unique chemical properties.

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Following are the most significant chemical properties contained by Chitosan.

• Linear poly-D-glucosamine

• Chelating effect on numerous passage- metal ions

• Assists in protein separations

• Offer fungistatic and Basteriostatic effects

• Full capacity of reaction with amino groups

Moreover, studies of Chitosan chemistry have found a motivating aspect about the viscosity of Chitosan. According to this research the Chitosan viscosity is mainly reliant on average molecular weight of Chitosan itself. Chromatography together with technique of light scattering detection is the best possible way of determining this molecular weight.

Amino group is another prime ingredient of Chitosan polymers as reported by the several studies conducted to ascertain the precise Chitosan chemistry. Chitosan is a sort of positively charged polymer having about 6.5 pKa value of amino group and as a consequence these are easily soluble in acidic in addition to neutral solutions. This research about Chitosan chemistry has in addition concluded that Chitosan polymer either artificially made or naturally available is a bio-adhesive.

This is as it can easily and quickly binds up with surfaces having negative charges on them – for instance, mucosal membranes. It has been concluded by analysts after going through an array of studies about Chitosan chemistry that Chitosan may be utilized in a lot of commercial applications.

Body Balance Chitosan – The Miracle Fiber

A major problem that affects nearly half the population of earthlings is obesity or excess weight. Studies have reported that children too are not immune to excess weight gain. Well, proper levels of circulating blood fats are very necessary for better health. The body naturally has a means of governing the production and removal of these lipoproteins to keep them at healthy levels. Nonetheless, if these levels become high and the cholesterol ‘set points’ attempts to reduce the cholesterol levels through diet alone, it will be defeated by your own body’s manufacture of cholesterol. It then follows that your system needs to look after its improper ‘set point’.

Chitosan is a regular fiber resulting from the shells of crustaceans like shrimps, lobsters and crabs, is now considered as the greatest effective answer to maintain a well-balanced body. Hence lots of people call it as ‘body balance chitosan’ which monitors the levels and quantities of circulatory fats, obstructing the fats in the gastrointestinal tract, thus reducing the bad cholesterol while providing the suitable effect which can aid the natural manufacture of the body’s good cholesterol.

How Does Body Balance Chitosan Assist Weight Loss?

Body balance chitosan is an indigestible fiber which passes through the digestive system without being absorbed and without contributing any calories. As maintained by a few claims, body balance chitosan binds to dietary fats, preventing them from being absorbed into the body. This is actually the primary function of chitosan that has gained so much interest among those who are trying to slim down, yet maintain a stable body.

Further worth noting is the claim that when you consume food that incorporates fat, the body finds it easier to store those fats than to make use of them for body fuel. Also, both the fats and lipids are absorbed into the blood stream. They then carry cholesterol around the body where it can collect in arteries, veins and around organs. It is during this stage actually that the arterial blockages, fatty liver and other serious health issues can happen.

Imaginably what’s wonderful about the said body stability chitosan is that the fat attached to it cannot make its way into the bloodstream or be retained inside the body as a fuel source. This is because fat along with chitosan now forms a fat ball that is too big to pass through the lining between the gastrointestinal tract and the bloodstream. It has been determined that about sixty six percent of the fat content of a meal can be absorbed by body balance chitosan. And, as the blocked fat failed to enter into the gastrointestinal tract and the blood stream, it is then eliminated through the bowel.

What Chitosan Can’t Do?

Note that chitosan works perfectly for a stable body if you will combine it with exercise at medium intensity and nutrient like the Carnitine which boosts fat burning and energy levels. To put it simply, a body balance chitosan cannot make you lose fat that is already stored in the tissues of the body.